Understanding Canine Cushing's Disease: Symptoms, Diagnosis, and Treatment Options

June. 03,2025

Discover essential insights into canine Cushing's disease, including key symptoms, diagnostic procedures, and treatment options. Early detection and professional veterinary care are vital for managing this serious condition, which affects a dog's health and quality of life. Learn how to recognize symptoms like excessive panting, a pot-bellied appearance, and skin thinning, and understand the importance of proper diagnosis through blood tests and ultrasounds. Treatment approaches such as surgery, radiation, and supportive therapies can improve prognosis, emphasizing the need for prompt veterinary intervention.

Understanding Canine Cushing's Disease: Symptoms, Diagnosis, and Treatment Options

Understanding Canine Cushing's Disease: Symptoms, Diagnosis, and Treatment Options

Cushing's disease, also known as Cushing's syndrome, occurs when the adrenal glands near a dog's kidneys produce excessive cortisol hormone. While cortisol is vital for regulating body functions, abnormal levels can be dangerous. This condition can also affect dogs, so pet owners should watch for signs and seek veterinary care promptly. Keep reading to learn about the symptoms, diagnostic methods, and treatment options for Cushing's disease in dogs.

Signs to Watch For
Many symptoms of Cushing's can resemble other health issues, making diagnosis challenging. However, pet owners should consult a vet if their dog shows the following signs:

Heavy Panting
Normal panting helps dogs cool down or recover from exercise. Excessive and frequent panting, especially when not related to heat or activity, may signal Cushing's. Any persistent abnormal panting warrants a vet consultation.

Increased Thirst and Urination
Early indicators include drinking more water and urinating frequently. These signs can lead to accidents indoors and pose health risks. Veterinary diagnosis is essential to determine if these symptoms stem from Cushing's or other issues like kidney problems.

Swollen Belly
High cortisol levels can lead to increased appetite and a noticeable pot-bellied appearance caused by liver bloating or ligament relaxation. This can sometimes mimic other conditions such as fluid buildup, so veterinary assessment and ultrasound may be necessary.

Skin Thinning
Dogs with Cushing's often develop thin, fragile skin, especially around the sides. Elevated cortisol disrupts skin cell regeneration, leading to increased bruising, slow wound healing, and pigmentation changes. Additional symptoms may include hair loss, behavioral shifts, high blood pressure, and recurrent infections.

The severity and presentation of symptoms vary among dogs, developing gradually over time.

Diagnostic Procedures
Diagnosis requires multiple tests, including blood work and ultrasounds:

Blood Analysis
Blood tests can reveal elevated liver enzymes, high cholesterol, and reduced BUN levels, hinting at Cushing's.

Ultrasound Imaging
Ultrasounds examine the kidneys, liver, and adrenal glands for abnormalities or tumors, aiding diagnosis.

Additional tests like the Low-Dose Dexamethasone Suppression Test (LDDST) and ACTH stimulation test help confirm the diagnosis, depending on the individual case.

Managing Cushing's in Dogs
There is no standardized cure; treatment varies based on symptoms and severity. Common approaches include surgery and radiation therapy:

Surgical Intervention
Surgery may be performed if adrenal tumors are detected; benign tumors are often removable, leading to potential cure. Difficulties arise with pituitary tumors, which are harder to access. Due to slow healing in affected dogs, vets often opt for alternative treatments.

Radiation Therapy
Radiation targets pituitary tumors to shrink their size. This non-invasive option can alleviate neurological symptoms and improve prognosis. The process involves multiple sessions over several weeks and may cause side effects like hair and skin pigment loss near the treated area.

In severe cases, vets might recommend acupuncture, specialized diets, and natural remedies to support overall health during treatment.


Important Note:

The information provided is for educational purposes and should not replace professional veterinary advice. If your dog exhibits any symptoms discussed, seek veterinary consultation promptly. Treatment plans should always be tailored by qualified professionals to ensure the best outcomes for your pet.