Understanding Osteoarthritis: Signs and Contributing Factors

April. 25,2025

This article explores osteoarthritis, highlighting key risk factors such as age, gender, genetics, obesity, and previous joint injuries. Common symptoms like joint pain, stiffness, and swelling are also discussed. Maintaining joint health through proper management of modifiable risks and early intervention can help reduce the impact of this degenerative condition. Learn about the significance of physical activity, diet, and ergonomic practices in preventing OA progression. Stay informed to better manage or prevent osteoarthritis and improve quality of life.

Understanding Osteoarthritis: Signs and Contributing Factors

Understanding Osteoarthritis: Signs and Contributing Factors

Risk Elements Associated with Osteoarthritis

Osteoarthritis development is influenced by various factors categorized into three groups: adjustable local factors, adjustable systemic factors, and non-adjustable systemic factors.

Adjustable local factors include influences near the affected joint that can be modified, such as muscle strength, activity levels, prior joint injuries, joint alignment, and leg length discrepancies.

Adjustable systemic factors involve broader health aspects that can be managed, including obesity and diet choices.

Non-adjustable systemic factors are inherent characteristics that cannot be changed, like age, gender, genetics, and ethnicity.

1) Age

Advancing age is a primary risk factor because prolonged use causes joint wear and tear. Women aged 60-64 are particularly susceptible. Age-related changes like decreased joint tissue adaptability, increased bone turnover, and oxidative damage contribute to higher OA risk.

2) Gender

Women tend to develop OA more often and experience more severe symptoms, especially after menopause. Commonly affected areas include hands, feet, and knees, influenced by hormonal and structural differences.

OA susceptibility also has a genetic component. Over half of hip, hand, and knee OA cases are linked to genetic factors, with specific chromosomes identified as contributors.

In younger adults, joint injuries leading to post-traumatic OA are significant causes.

3) Obesity

Excess weight increases the risk of knee and hip OA, with stronger correlations observed in women. For every 5-point BMI increase, knee OA risk rises by 35%. Weight loss notably reduces OA risk.

4) Diet

Low vitamin D and antioxidant levels, such as vitamin C, may elevate OA risks by impairing bone and cartilage health or allowing oxidative damage. Maintaining adequate vitamin levels is suggested to help mitigate progression.

5) Physical Activity and Occupational Factors

Repetitive joint movements and occupations involving squatting, kneeling, standing, or lifting heighten OA development chances. Sports and repetitive tasks can increase joint stress and injury risk, though running does not show a significant link to knee or hip OA.

6) Past Joint Injuries

Traumas like ACL tears or meniscal damage are strongly associated with early OA. These injuries cause tissue damage and misalignment, leading to degenerative changes over time.

7) Muscle Weakness

Weak muscles fail to stabilize and absorb joint loads, raising OA risk and progression. Strengthening exercises can decrease the likelihood of developing or worsening OA.

8) Joint Alignment

Recognizing Osteoarthritis Symptoms

OA symptoms develop gradually and worsen over time, including:

Pain during or after joint activity

Persistent ache

Sensitivity to touch

Stiffness after rest or sleep

Limited joint mobility

Grinding or cracking sounds during movement

Bone spurs near the joint

Swelling of joint tissues

Symptoms vary depending on the affected joint. Hip OA causes groin and buttock pain, while knee OA often produces grinding sensations. Hand OA presents with swelling, bone spurs, and pain at finger joints and the thumb base. Foot OA results in pain at the big toe base. These symptoms can impair mobility and increase fall risk.