Managing Dyskinesia: Treatment Strategies and Care Approaches

Approaches to managing dyskinesia

Addressing dyskinesia can be complex, depending on how advanced the condition is. Some individuals may discontinue levodopa, which is often linked to dyskinesia, but this can lead to a resurgence of symptoms like tremors and rigidity. Doctors usually aim to find a balance, adjusting medication doses carefully. Others choose to continue levodopa to avoid Parkinson's complications, despite the risk of dyskinesia. Various treatments include medication adjustments, motor monitoring, and dietary modifications to improve quality of life.

Treatment options for dyskinesia include various therapeutic approaches.

Medication Management

Using controlled-release formulations of levodopa helps prevent peak-level side effects. Splitting daily doses into smaller, more frequent administrations can maintain steadier medication levels. Drugs that slow down levodopa metabolism, or using levodopa-carbidopa gel directly applied to the intestine, can promote more consistent dopamine levels. Additionally, medications like amantadine, a glutamate antagonist, can help regulate dopamine by controlling glutamate activity, and can be taken orally or intravenously.

Keeping a motor diary is essential for tracking medication effectiveness. Patients record dosages, meal times, symptom onset, and fluctuations, which helps doctors tailor treatment plans. Diet also plays a role; protein-rich foods may interfere with levodopa absorption. Taking medication 30 minutes before meals or adjusting protein intake to the evening can improve drug efficacy. Always consult a healthcare professional before making dietary changes.