Lexus RX 350 vs. Acura MDX: Which Mid-Size SUV Reigns Supreme?

July. 16,2025

This detailed comparison between the Lexus RX 350 and Acura MDX highlights their features, interior, performance, and practicality to help buyers choose the best luxury mid-size SUV for their needs. Both vehicles offer excellent value, with differences primarily in seating capacity and cargo space, making them suitable options for different families. The review provides insights into interior comforts, engine efficiency, and key aspects to consider before purchasing.

Lexus RX 350 vs. Acura MDX: Which Mid-Size SUV Reigns Supreme?

Comparing the Lexus RX 350 and Acura MDX: Which Is the Top Choice?

In the competitive world of luxury mid-size SUVs, Toyota and Honda showcase their offerings with the Lexus RX 350 and Acura MDX. Both vehicles are designed to deliver comfort, performance, and practicality. Discover how these models stack up regarding features, interior design, and driving experience to determine which suits your needs best.

Lexus RX 350
The Lexus RX 350 appeals to those seeking an uncomplicated yet reliable SUV. It features a robust V6 engine, ensuring a smooth and comfortable ride, ideal for city commuting. However, it may not perform well on steep inclines or rugged terrain.

Lexus RX 350 vs Acura MDX

The 2017 Lexus RX 350 is known for its practicality and straightforward design. It comfortably seats five passengers with a well-crafted interior featuring quality upholstery. The vehicle offers ten-way power-adjustable front seats, available heated and ventilated options, as well as power-folding rear seats. Cargo capacity is modest, with foldable rear seats providing extra space but limiting overall volume.

The infotainment system offers adequate functionality, aligning with the vehicle's price point.

Acura MDX
Unlike the RX 350, the Acura MDX caters to larger families with its seven-passenger capacity. It boasts more cargo space and holds comparable interior quality and engine performance, both equipped with similar powertrains. The MDX offers an estimated fuel economy of 20 mpg city and 27 mpg highway, making it efficient for daily driving.

Comparing the 2017 Lexus RX 350 and Acura MDX reveals minimal differences, primarily in seating capacity and cargo space. Both models provide excellent value in the luxury crossover segment, with reasonable pricing considering their features and performance. Reading detailed reviews of each vehicle can assist buyers in making an informed decision.