Guidelines for Using Opioids in Managing Chronic Pain

July. 16,2025

This article provides comprehensive guidance on the safe use of opioids for pain relief, emphasizing risks of dependence, side effects, and alternatives for managing chronic pain. It highlights when opioids are appropriate, costs involved, and the importance of medical supervision to avoid misuse and complications, ensuring readers make informed decisions about their pain management options.

Guidelines for Using Opioids in Managing Chronic Pain

Guidelines for Using Opioids in Managing Chronic Pain

Opioid medications, commonly known as narcotics, are frequently used for pain relief. They are effective for acute discomfort, such as post-surgical pain or injuries like broken bones, and can also alleviate severe cancer-related pain.

However, unlike other medicines, opioids are potent drugs and are generally not recommended for persistent, long-term conditions like frequent headaches, arthritis, or lower back pain—collectively termed "chronic" pain. If you consider opioids for prolonged pain management, consult your healthcare provider to explore safer or alternative options.

Guidelines for Opioid Use in Chronic Pain
Here's why:

Overprescription of opioids

Many patients visit doctors with ongoing pain, often being prescribed opioids. Recently, there has been a significant rise in opioid prescriptions for chronic conditions, which can lead to serious side effects and dependency.

Common opioids include:

  • Hydrocodone (e.g., Vicodin)
  • Oxycodone (e.g., OxyContin, Percocet)

While effective for short-term pain, their long-term efficacy for persistent pain remains uncertain.

Potential side effects and dangers

Repeated use can lead to physical dependence, where the body develops tolerance, requiring higher doses. Risks include:

  • Constipation
  • Vomiting
  • Nausea
  • Itching
  • Urinary retention
  • Respiratory issues
  • Mental confusion

Prolonged use increases addiction risk—about 25% of users face dependency. Overdose can be fatal, with approximately 46 deaths daily from accidental overdose.

Cost considerations

Some opioids like oxycodone can be quite expensive, costing over $1,000 monthly. Those without adequate insurance might find this prohibitively costly, and adverse effects might lead to additional expenses.

Alternative pain management options

Healthcare professionals recommend trying other therapies first, such as:

  • Corticosteroids and other safe medicines
  • Physical therapy, massage, exercise, spinal adjustments, acupuncture
  • Non-steroidal anti-inflammatory drugs (NSAIDs) and anti-seizure medications (with caution)

When should opioids be used?

For severe cancer pain, opioids are appropriate, especially when pain significantly impacts quality of life. For other types of chronic pain, use them only if pain is intense, and under regular medical supervision.

If other treatments fail and pain is severe, opioids may be considered as a short-term solution.

Important advice if prescribed

Discuss potential side effects and risks with your doctor. Follow prescribed dosages carefully and monitor for signs of dependence, such as cravings or mood swings.