Top 6 FDA-Approved Drugs for Managing High Cholesterol

May. 18,2025

This article reviews six FDA-approved medications for high cholesterol management, highlighting their functions and target patients. It emphasizes combining medication with lifestyle changes for optimal health and underscores consulting healthcare professionals for personalized treatment plans.

Top 6 FDA-Approved Drugs for Managing High Cholesterol

Top 6 FDA-Approved Drugs for Managing High Cholesterol

Understanding FDA-Approved Treatments for High Cholesterol

High cholesterol causes fatty buildup in arteries, obstructing blood flow and increasing the risk of strokes and heart attacks. Causes can be genetic or lifestyle-related, but the condition is both preventable and treatable. Lifestyle changes like a healthy diet and regular exercise can help control cholesterol. For severe cases, physicians may prescribe specific medications to manage levels effectively.

Several FDA-approved medications assist in managing high cholesterol, but they should only be taken under medical supervision.

Kynamro
Kynamro reduces bad cholesterol such as non-HDL, apo-B, and LDL, especially for individuals with homozygous familial hypercholesterolemia. It is most effective when combined with a low-fat diet and prescribed treatments but does not necessarily lower heart disease risk.

Altoprev
Altoprev helps lower LDL cholesterol while increasing HDL levels, reducing triglycerides that contribute to cardiovascular problems. Its use can help lower risks of heart attacks, strokes, and complications linked to diabetes when paired with a healthy lifestyle.

Repatha®
Repatha® is a monoclonal antibody aiding the liver in lowering LDL cholesterol. It is recommended for individuals with heterozygous familial hypercholesterolemia (HeFH) and those at high risk for heart attacks or strokes, used alongside diet and other treatments.

PRALUENT
PRALUENT enhances liver function to decrease LDL cholesterol, especially for patients with heterozygous familial hypercholesterolemia or those who suffered cardiovascular events due to high cholesterol.

Colestid Flavored
As a bile acid-binding resin, Colestid Flavored reduces LDL by removing bile acids, encouraging the liver to use cholesterol to produce more bile acids, lowering overall cholesterol when combined with diet and medication.

Antara
Antara (Fenofibrate) decreases LDL and triglycerides while boosting HDL. It promotes fat breakdown in the blood, and its effectiveness improves with diet and exercise, avoiding smoking and unhealthy habits.

Note:

The information provided about symptoms, treatments, and side effects is for educational purposes only. It should not replace professional medical advice. Always consult licensed healthcare providers for diagnosis and treatment options.