Top 5 Medications for Heartworm Prevention in Dogs

June. 25,2025

Discover the top five medications for preventing heartworm in dogs, including chewables and injections. These trusted drugs protect against multiple parasites like heartworms, hookworms, and roundworms. Administering these medicines regularly can keep your furry friend safe from severe health complications. Consult your veterinarian for guidance on choosing the best preventative medication based on your dog's age, breed, and health status. Staying proactive with heartworm prevention is crucial for your pet's long-term well-being and happiness.

Top 5 Medications for Heartworm Prevention in Dogs

Top 5 Medications for Heartworm Prevention in Dogs

Heartworm disease is a serious parasite infection transmitted by mosquitoes, affecting a dog's lungs and heart. Symptoms can be severe, often requiring urgent veterinary care and hospitalization. Recovery may take months of rest. Preventative measures are crucial for dog owners to avoid infection.

Below are key medications commonly used to prevent heartworm in dogs:

Simparica Trio® - A widely used chewable that prevents multiple parasites including heartworms, stomach worms, hookworms, and roundworms. It is suitable for pups from eight weeks old.

This medication is administered as a chewable tablet.

Heartgard Plus - An oral beef-flavored medication containing ivermectin and pyrantel pamoate, effective against heartworms, hookworms, and roundworms, making it a top choice among dog owners.

Tri-Heart® Plus - A cost-effective alternative used to prevent heartworms and protect against other intestinal parasites, compatible with all dog breeds.

Moreover, Tri-Heart Plus is known for its safety and affordability, providing effective protection against heartworms and additional parasites like roundworms, hookworms, and whipworms.

Iverhart Plus - Similar to Simparica Trio, this chewable tablet ensures protection against heartworm and other parasites like hookworms and roundworms. Flavored for easy administration, it is typically given monthly. Always consult a veterinarian before use.

Proheart - An injectable option for cases where monthly pills aren't feasible. It contains moxidectin to guard against heartworms and hookworms. Due to potential side effects, injectables are usually reserved for specific situations.

Note:

Our site offers diverse information across many pet health topics. While helpful, this content should not replace professional veterinary advice. We disclaim responsibility for inaccuracies or variations in data across sources. Also, readers should explore current offers and schemes independently to find the best options for their pets.