Top 5 Risk Factors Associated with Mesothelioma Development

May. 26,2025

This article highlights the top five risk factors for mesothelioma, emphasizing asbestos exposure, genetically inherited traits, and environmental risks. Understanding these factors aids early detection and prevention of this aggressive cancer.

Top 5 Risk Factors Associated with Mesothelioma Development

Mesothelioma is a serious cancer with limited survival prospects, making early detection vital. Recognizing key risk factors can significantly improve prognosis through prompt intervention.

Below are the main contributors to mesothelioma risk:

Asbestos Exposure: Over 80% of mesothelioma cases are linked to asbestos. This mineral contains durable fibers that are fire-resistant and flexible. People involved in manufacturing, installation, or maintenance involving asbestos fibers are at high risk of inhalation or ingestion, leading to disease.

Zeolite Exposure: Zeolite, a mineral similar to asbestos, can pose risks if inhaled. Protective measures are recommended in work settings where zeolite dust may be present.

Radiation Therapy: High-dose radiation treatments, especially targeting chest or abdominal areas, have been associated with increased mesothelioma risk.

SV40 Virus Infection: Exposure to the SV40 virus, historically present in some polio vaccines, has been linked to higher mesothelioma rates.

Genetic Factors: Inherited genetic mutations, particularly in the BAP1 gene, account for approximately 1% of cases, passing disease risk from parent to child.

It is crucial to understand these risk factors for better prevention and early diagnosis. Always consult healthcare professionals for proper screening and advice.